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T9905 |
Cetuximab
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Cetuximab (anti-EGFR),C225 |
EGFR
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Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM). Cetuximab has antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis. |
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T21128 |
Lansoprazole sulfide
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Lansoprazole impurity C,AG-1777,EC 600-451-9,H 225/18,K-1252 |
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Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor. |
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T36944 |
Ara-G
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Nucleoside Antimetabolite/Analog
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Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate... |
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T36414 |
N-Nitroso Sarcosine
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N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2In vivo, N-nitroso sarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice... |
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T38269 |
Purfalcamine
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Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes mala... |
